Vinpocetine efuefu

Novema 5, 2020

Cofttek o le sili Vinpocetine paʻu gaosi i Saina. O la matou fale gaosi ei ai le maeʻa gaosiga gaosiga (ISO9001 & ISO14001), ma le masina gaosiga gafatia o 340kg.

Tulaga: I le Gaosiga o Gaosiga
Vaega: 1kg / ato, 25kg / Drum

Vinpocetine efuefu Sfaʻamatalaga

igoa: Vinpocetine
CAS: 42971-09-5
Mama Atoatoa i Tulaga 98%
Fua Faatatau Molecular: C22H26N2O2
Pauna Molecular: 350.454 g / mol
Melt Point: 147-149 ° C
Suafa: AY-27255, Cavinton, Eburnamenine-14-carboxylic acid, Ethyl Apovincaminate, Ethylapovincaminoate,
Fa'amatalaga: Ethyl Ester, RGH-4405, TCV-3b, Vinpocetin, Vinpocetina, Vinpocétine.
InChI Key: DDNCQMVWWZOMLN-IRLDBZIGSA-N
Aveesea Half Life: 2.54 +/- 0.48 itula
Solubility: Soluble i le DMSO, Methanol, Suavai
Tulaga o le Teuina: 0 - 4 C mo se taimi puʻupuʻu (aso i vaiaso), poʻo le -20 C mo se taimi umi (masina)
talosaga: Vinpocetine o se tuʻufaʻatasia mai le Periwinkle laʻau o loʻo faʻaaogaina o se mafaufau puipuia ma puipuia aneti-matua sooupu. Tasi o le sili atu taatele o le nootropics, Vinpocetine mafai faʻalauteleina le tafe toto ma ua touth e faʻateleina manatua; e leʻi suʻesuʻeina foi lenei tagi.
Faʻaaliga: Paʻu paʻu

 

Vinpocetine (42971-09-5) NMR Spectrum

Vinpocetine (42971-09-5) - NMR Spectrum

Afai e te manaʻomia le COA, MSDS, HNMR mo vaega taʻitasi o oloa ma isi faʻamatalaga, faʻamolemole faʻafesoʻotaʻi le matou maketi pule.

 

O le a le Vinpocetine (42971-09-5)?

Vinpocetine o se gaosia alkaloid gaosia mai le periwinkle laʻau (faʻapitoa, synthesized mai le mole mole lauiloa o le 'vincamine') e foliga mai o loʻo i ai se faʻamaumauga o faʻaogaina i atunuʻu o Europa mo le togafitia o le mafaufau faʻafuaseʻi, lavea faʻafouina, ma epilepsy. Vinpocetine e masani ona faʻaaogaina o se nootropic compound i le faʻamoemoe e ono faʻaosofia ai le manatuaina faʻavae.

 

Vinpocetine paula (42971-09-5) penefiti

Vinpocetine e le faʻaogaina atoa, ae o le mea e mitiia tumutumu i le toto vave ma faigofie ona ulufale i le faiʻai e mafai ai ona faʻaaoga ana gaioiga. O meatotino e foliga mai e faʻaoga i le fofoga vinpocetine faʻaopoopoga aofia ai neuroprotection (faʻasaga i vailaʻau ma sili atu faʻaosofia) ma faʻaititia neural pupuga, ae o le mafaufau faʻalauteleina aʻafiaga foliga mai e le lagolagoina lelei e molimau i lenei taimi o taimi. E ui o le vinpocetine e foliga mai e aoga tele i le puipuia o vailaʻau oona poʻo faʻafitauli mai le mafuaʻaga o le amnesia, e le o faʻaaliaina e faʻaleleia atili ai le manatuaina o mea na fausiaina.

Vinpocetine e aliali mai foi e i ai sona aoga i le mafaufau faʻaleagaina, ae o le aofaʻi o tusitusiga i lenei mataupu e sili laitiiti nai lo isi fualaʻau faʻataʻitaʻia mo lenei faʻamoemoe (CDP-Choline poʻo Alpha-GPC faʻapitoa). Le itiiti ifo ma le tasi suʻesuʻega ua maitauina le faʻaleleia o le tali atu i taimi ma le 40mg laupapa o le vinpocetine, lea e mafai ona avea ma se tasi o na o le toetoe lava talafeagai talafeagai faʻaleleia mo soifua maloloina tagata i lenei taimi o taimi.

Infusions o vinpocetine e foliga mai e faʻamalosia ai le tafe o le toto i le faiʻai e aunoa ma le masani ai e fesuiaʻi le mamafa o le tino i le tino, ma o lenei e mafaufauina (ae le faʻaalia) e faʻaoga i le fofoga taumafa. O lenei mea e ono faʻaititia ai le tiga o le ulu e mafua mai i le soʻona omiga, ma e tusa ma le faʻaaogaina masani o le periwinkle toto (e faʻaititia ai le tiga o le ulu).

 

Vinpocetine (42971-09-5) talosaga?

O auala ole vinpocetine e tele. E foliga mai e fesoʻotaʻi ma tele ion auala (sodium, potassium, ma kalisiu) aʻo taumafai e iʻu i le suppressive aʻafiaga i le neurotransmitter faʻasaʻolotoina ma le neuroprotection pe a taofia le dopamine poʻo le glutamate (o nei lua, pe a le faʻamalosia e fualaʻau, e ono mafua ai oxidative faʻaleagaina). E faʻafesoʻotaʻi foʻi ma le alpha adrenergic receptor ma le TPSO receptor, ma e ui e le o mautinoa le penefiti o nei receptor interactions e ono talafeagai talu ai na tutupu i le tutusa concentrations o le ion channel interactions faia.

Vinpocetine o se tasi e taofia le PDE1, o se masini e mafai ona faʻaaoga e faʻamalosi ai le mafaufau ma faʻalauteleina ai le mafaufau. Ae paga lea, o lenei taofi e tupu i se lapoʻa tele ma e ono le faʻaaogaina i fua masani o vailaʻau o le vinpocetine.

Tutusa ma PDE1, o se antidopaminergic mafai o le vinpocetine ma le taofiofia o le glutaminergic taliaina e foliga mai uma e tupu i le maualuga maualuga faʻatulagaina i vitro ma ono ono le talafeagai i tulaga masani faʻaopoopoga.

 

Vinpocetine (42971-09-5) Totoga

Vinpocetine o loʻo ave i aso uma metotia o le 15-60mg, vaevaeina i tolu aso i aso tofo ma taumafataga. O le fua maualalo fualaʻau o le 5mg i nei meaʻai uma e tolu, ma le 20mg i taumafataga uma e vaʻaia o le maualuga maualuga o le aoga. O nei inumaga e faia mo le faʻamoemoega o le neuroprotection, faʻalauteleina le cerebral toto tafe, ma faʻaititia le fua o le mafaufau faʻafuaseʻi.

O metotia i le pito i luga maualuga o lena tulaga (30-45mg ogaoga vailaʻau) atonu e aoga mo le faʻalauiloaina o le malamalama ma manatuaina faʻavaeina i se isi itu maloloina tagata, ae leai se tele o faʻamaoniga vaʻai i lenei tagi.

Lapataiga: mo fafine maʻitaga, o le tutusa o vailaʻau faʻaaogaina 10 mg / d ua fesoʻotaʻi ma fetal oona i manu suesuega. 10 mg / d atonu e ono aʻafia, a e maise pe a e faia i le taimi atoa o le maʻito.

 

Vinpocetine paʻu mo le faatauina atu(O fea e faʻatau ai le pauta Vinpocetine i le tele)

O le matou kamupani e fiafia i mafutaga vavalalata ma a matou paʻaga aua matou te taulai atu i auaunaga a tagata faatau ma tuʻuina atu oloa sili. Afai e te fiafia i la matou oloa, matou te fesuisuiaʻi ma le faʻaleigaina o poloaiga e fetaui ma lou manaʻoga patino ma lo matou taimi faʻataʻitaʻi vave i poloaiga e mautinoa o le a sili ona e tofoina a matou oloa i le taimi. Matou te taulai atu foi i auaunaga faaopoopo-faaopoopo. Matou te avanoa mo fesili fesoasoani ma faʻamatalaga e lagolago ai lau pisinisi.

O matou o se polofesa Vinpocetine paʻu sapalai mo le tele o tausaga, matou te sapalaiina oloa ma tauvaga tau, ma o a matou oloa o le sili ona maualuga lelei ma faia faigata, tutoʻatasi suʻesuʻega ina ia mautinoa ai e saogalemu mo taumafa i le lalolagi atoa.

 

mau faasino
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  2. Akopov SE, Gabrielian ES. Aʻafiaga o le aspirin, dipyridamole, nifedipine ma Cavinton o gaioiga i luga o le lapisi faʻaputuga faʻatosinaina e eseʻese agavaʻa soʻosoʻatasi soʻosoʻo ma tuʻufaʻatasia. Eur J Clin Pharmacol. 1992; 42 (3): 257-259.1577042
  3. Alkuraishy HM, Al-Gareeb AI, Albuhadilly AK. Vinpocetine ma pyritinol: o se fou faʻataʻitaʻiga mo le toto rheological fesuiaʻiga i cerebrovascular faʻafitauli-o se randomized pulea falemaʻi suʻesuʻega. Biomed Res Int. 2014; 2014: 324307.25548768.