Sodium Citicoline (33818-15-4)

Ia 8, 2021

Cofttek o le sili ona lelei Citicoline Sodium (CDP Choline Sodium) fai pauta i Saina. O la matou fale gaosi ei ai le maeʻa gaosiga gaosiga (ISO9001 & ISO14001), ma le masina gafatia gaosiga o 220kg.

 


Tulaga: I le Gaosiga o Gaosiga
Vaega: 1kg / ato, 25kg / Drum

Sodium Citicoline (Sodium Chine CDP)(33818-15-4) Sfaʻamatalaga

igoa: Sodium Citicoline (Sodium Chine CDP)
CAS: 33818-15-4
Mama Atoatoa i Tulaga 98%
Fua Faatatau Molecular: C14H25N4NaO11P2
Pauna Molecular: 510.308 g / mol
Melt Point: > 240 ° C
Suafa: Sodium Citicoline; Cdp-choline sodium
Fa'amatalaga: Sodium [[(2S,3R,4S,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]2-(trimethylazaniumyl)ethyl phosphate
InChI Key: YWAFNFGRBBBSPD-KDVMHAGBSA-M
Afa Ola: 56 itula
Solubility: Soluble i le DMSO, Vai (Lemu laititi)
Tulaga o le Teuina: Faʻamago, pogisa ma i le 0 - 4 C mo se taimi puʻupuʻu (aso i vaiaso) poʻo le -20 C mo se taimi umi (masina i tausaga).
talosaga: Citicoline Sodium o se sui o le neuroprotective ma meaʻai faʻaopopo
Faʻaaliga: Paʻu Paʻu Paʻu

 

Sodium Citicoline (33818-15-4) NMR Spectrum

Sodium Citicoline (33818-15-4) NMR Spectrum

Afai e te manaʻomia le COA, MSDS, HNMR mo vaega taʻitasi o oloa ma isi faʻamatalaga, faʻamolemole faʻafesoʻotaʻi le matou maketi pule.

 

O le a Sodium Citicoline (Sodium Chine CDP)(33818-15-4) ?

Sodium Sodium (CDP-choline Sodium, cytidine 5'-diphosphocholine) paʻu o se suavai soluble suavai e avea o se muamua i uma choline ma cytidine totonu o le faiʻai (lea mulimuli ane liua i uridine). I tagata, o le Citicoline Sodium ose mea taua tele o lona aoga i le faʻaititia o aʻafiaga o le neural tube, fatty ate, ma isi faʻamaʻi ua uma ona tusia. O le CDP-choline Sodium o se tasi o le tolu choline-o loʻo iai phospolipids e mafai ona faʻaopoopo i le tautala (o isi e lua o le alpha-GPC ma le phosphatidylcholine).

 

Sodium Citicoline (Sodium Chine CDP)(33818-15-4) faamanuiaga

O le CDP-choline e faʻagaoioia le biosynthesis o fausaga phospholipids i neura membrane, faʻateleina ai le faʻatupuina o le cerebral metabolism ma galue ai i tulaga o isi neurotransmitters. O lea la, ua faʻataʻitaʻia faʻataʻitaʻia o le CDP-choline faʻateleina noradrenaline ma dopamine maualuga i le CNS.

O lenei faʻaopoopoga ua tuʻuina atu i le puipuia poʻo le togafitia o faaletonu o mafaufauga e fesoʻotai ma le matua ona o le mea moni o faʻamalama uma e lua e faʻamaonia e le neuroprotective ma mafai ona faʻaleleia le aʻoaʻoina. E foliga mai e sili atu le aoga nai lo le phosphatidylcholine (PC) i lenei matafaioi, i se vaega ona o le faateleina foi o le tuufaatasiga o PC i le faiʻai, o lona malosi e foliga tutusa ma le Alpha-GPC.

 

Sodium Citicoline (Sodium Chine CDP)(33818-15-4) faaaogaina

O le CDP-choline e iai isi mea e ono faʻaaoga e faʻatatau i le iloa. E masani ona faʻaaogaina o se mea e faʻaleleia ai le mafaufau i le autalavou, ae e ui lava i nisi o aʻoaʻoga a le aʻoga o loʻo fautua mai ai e mafai lenei mea ile gutu CDP-choline, e leai ni suʻesuʻega a tagata i talavou i lenei taimi ole taimi. O se tasi suʻesuʻega na maitauina le faʻaopopoina o le uaʻi ma le maualalo o le vailaʻau CDP-choline (lea e manaʻomia le toe faia), ma le CDP-choline ono i ai ni matafaioi o se anti-addict compound e faʻasaga i cocaine ma (faʻamaoniga muamua faʻamaonia) meaʻai foi.

 

Sodium Citicoline (Sodium Chine CDP)(33818-15-4) talosaga

Citicoline Sodium (CDP Choline Sodium) pauta o se sui sooupu neuroprotective. E galue e ala i le faʻalauteleina o feʻaveaʻi fesoʻotaʻiga, faʻaosofia le tuʻufaʻatasia o SAMe, ma faʻateleina glucose metabolis. Citicoline Sodium (CDP Choline Sodium) o le pauta o se mea e tupu mai ai le nucleotide; ogatotonu ile auala tele ole lecitin biosynthesis. Neuroprotective. E faʻaaogaina ile togafitia ole ischemic stroke ma le ulu tiga. Neuroprotectiveproduct. Citicholine faʻaalia puipuiga puipuiga i cerebral ischemia, afaina ai le faiʻai faiʻai, ma le manatuaina faʻafitauli. Talu ai nei na faʻaalia ai le aoga tele e faʻasaga i le dementia ina ua tuʻuina atu i le AchEIs (Acetylcholinesterase inhibitor). Faʻaalia Neuroprotective, acnticonvulsant gaioiga ma faʻamalieina aafiaga i se fualaʻau o 150mg / kg i isumu. Faʻaalia le puipuiga mai le alumini faʻamalosia le mafaufau leaga i isumu faʻaititia maualuga maualuga glutamate tulaga, oxidativestress ma LEAI soʻona gaosia i le hippocampus.

 

Sodium Citicoline (Sodium Chine CDP)(33818-15-4) paʻu mo le faatauina atu

(O fea e faʻatau ai le Sodium Citicoline (CDP Choline Sodium)(33818-15-4) efuefu tele)

O le matou kamupani e fiafia i mafutaga vavalalata ma a matou paʻaga aua matou te taulai atu i auaunaga a tagata faatau ma tuʻuina atu oloa sili. Afai e te fiafia i la matou oloa, matou te fesuisuiaʻi ma le faʻaleigaina o poloaiga e fetaui ma lou manaʻoga patino ma lo matou taimi faʻataʻitaʻi vave i poloaiga e mautinoa o le a sili ona e tofoina a matou oloa i le taimi. Matou te taulai atu foi i auaunaga faaopoopo-faaopoopo. Matou te avanoa mo fesili fesoasoani ma faʻamatalaga e lagolago ai lau pisinisi.

O matou o polofesa Sodium Citicoline (Sodium Chine CDP)(33818-15-4) Paʻepaʻe sapalai mo le tele o tausaga, matou te sapalaiina oloa ma tauvaga tau, ma o a matou oloa o le sili ona maualuga lelei ma faia faigata, tutoʻatasi suʻesuʻega ina ia mautinoa ai e saogalemu mo le taumafaina i le lalolagi atoa.

 

mau faasino

[1] Tyurenkov IN, Kurkin DV, Bakulin DA, Volotova EV, Chafeev MA. [Cerebroprotective gaioiga o metformin, gosogliptin, citicoline ma se tala GPR119 agonist i serebral ischemia i lalo o le maʻi suka mellitus]. Zh Nevrol Psikhiatr Im SS Korsakova. 2017; 117 (12. Vyp. 2): 53-59. doi: 10.17116 / jnevro201711712253-59. Lusia. PubMed PMID: 29411746.

[2] Jiang JJ, Xie YM, Zhang Y, Zhang YK, Wang ZM, Han B. [Fomai vailaau uiga o Shuxuening tui i togafitiga o serebral infarction suesuega e faavae i luga o le lesitala]. Zhongguo Zhong Yao Za Zhi. 2016 Tesema; 41 (24): 4516-4520. doi: 10.4268 / cjcmm20162407. Saina. PubMed PMID: 28936832.

[3] Liu Y, Wang J, Xu C, Chen Y, Yang J, Liu D, Niu H, Jiang Y, Yang S, Ying H. E lelei tele le gaosia o le CDP-choline gaosi CDP-koline faʻataʻitaʻiina e le ATP donor module. Ole Appl Microbiol Biotechnol. 2017 Fep; 101 (4): 1409-1417. doi: 10.1007 / s00253-016-7874-0. Epub 2016 Oketopa 13. PubMed PMID: 27738720.

[4] Giménez R, Raïch J, Aguilar J (Nov 1991). "Suiga i le faiʻai striatum dopamine ma acetylcholine taliaina e faʻatosina e le masani CDP-choline togafitiga o le matutua isumu". British Journal o Fale Talavai. 104 (3): 575–8. fai: 1111 / j.1476-5381.1991.tb12471.x. PMC1908237PMID1839138.

[5] Tardner, P. (2020-08-30). "O le faʻaaogaina o le citicoline mo le togafitia o le mafaufau pa'ū ma le mafaufau le atoatoa: A meta-auiliiliga o vailaʻau vailaʻau • Faʻavaomalo Faʻavaomalo o Siosiomaga Saienisi & Tekonolosi". Tusi Faʻavaomalo o Saienisi Siosiomaga & Tekonolosi. Toe aumai 2020-08-31.