Coluracetam (135463-81-9)

Coluracetam (135463-81-9) Sfaʻamatalaga

Coluracetam (135463-81-9) NMR Spectrum

Afai e te manaʻomia le COA, MSDS, HNMR mo vaega taʻitasi o oloa ma isi faʻamatalaga, faʻamolemole faʻafesoʻotaʻi le matou maketi pule.

O le a Coluracetam (135463-81-9)?

Laʻu pulupulu o le Coluracetam (MKC-231) o se vailaau gaosia o le racetam synthetic ua faamoemoe e avea o se kulupu nootropic. E le i ai se vaega tele o faʻamaoniga e suʻesuʻeina ai, ae o faiga o gaioiga (faʻapitoa foi ma le faʻatulagaga) e foliga mai e matuā vaʻavaʻavaʻai mai i isi mea faʻapitoa e pei o Piracetam poʻo Aniracetam.

Laititi Coluracetam pauu e foliga mai e fegalegaleai ma se gaioiga e taʻua o le maualuga o le filifiliina o le laina o le laina (HACU mo le pupuu), o le laasaga o le limite o le tusia o le lisiina i totonu o le neuron mo le fausiaina i le neurotransmitter acetylcholine. O le faateleina o le maualuga o le HACU e foliga mai e faateleina ai le gaioiga o neu suauu, o le mea lea o se sini manaomia mo le faaleleia atili o le mafaufau.

Coluracetam (135463-81-9) faamanuiaga

• Faʻaleleia Manatua ma Aʻoaʻoina
• Faʻaleleia Faitauga Malamalama ma Free Recall
• Taimi Mautinoa Siitia Siitia
• Faʻaititia Togafitiga-Puipuiga o le Paʻu
• Avanoa faʻamalosia Neurogenesis
• Mafai faʻalelei Mental Disability
• Ia Faʻalelei Faʻalelei
• Faʻaleleia le faʻailoga o le Irritable Bowel Syndrome
• Coluracetam faʻafiafiaga faʻaaoga

Coluracetam (135463-81-9) faaaogaina

Coluracetam (INN) (code name BCI-540; muamua MKC-231) paʻu o se nootropic sooupu o le racetam aiga. Na muamua atiaʻe ma faʻataʻitaʻia e le Mitsubishi Tanabe Pharma Corporation mo le faʻamaʻi o le Alzheimer. I le maeʻa ai o le vailaʻau le manuia e oʻo atu i faʻaiuga o ana falemaʻi faʻataʻitaʻi sa laiseneina e BrainCells Inc mo suʻesuʻega i le tele o faʻanoanoaga faʻaletonu (MDD), lea na muamua atu i le faʻailogaina o le "Qualifying Therapeutic Discovery Program Grant" e le setete o Kalefonia.

Coluracetam (135463-81-9) Totoga

O le tele o suʻesuʻega i luga o le coluracetam na faia i luga o manu nai lo tagata, o lea e leai ni taʻiala taʻitasi taliaina. O le gaosiga o gasegase masani e masani ona faamatalaina o le 5-20 mg. O tagata faaaoga i le coluracetam ua lipotia mai le tele o vailaau e faia uma i le tautala ma le faʻaogalua.

Faʻamatalaga a le tagata faʻaaoga ua taua foi o le faʻapalepale ile coluracetam paula e mafai ona vave tupu. E pei lava o vailaʻau uma, aemaise lava nootropics, e sili ona amata ile laʻititi o tui ae faʻasolo malie le fualaʻau a o tali atu lou tino ma faʻasaʻo ia vailaʻau. Coluracetam e le oona ma e manatu e faʻapalepale ma saogalemu.

Coluracetam laupepa mo le faatauina atu(O fea e faʻatau ai le pauta Coluracetam i le tele)

O le matou kamupani e fiafia i mafutaga vavalalata ma a matou paʻaga aua matou te taulai atu i auaunaga a tagata faatau ma tuʻuina atu oloa sili. Afai e te fiafia i la matou oloa, matou te fesuisuiaʻi ma le faʻaleigaina o poloaiga e fetaui ma lou manaʻoga patino ma lo matou taimi faʻataʻitaʻi vave i poloaiga e mautinoa o le a sili ona e tofoina a matou oloa i le taimi. Matou te taulai atu foi i auaunaga faaopoopo-faaopoopo. Matou te avanoa mo fesili fesoasoani ma faʻamatalaga e lagolago ai lau pisinisi.

O matou o se polofesa Coluracetam paʻu sapalai mo le tele o tausaga, matou te sapalaiina oloa ma tauvaga tau, ma o a matou oloa o le sili ona maualuga lelei ma faia faigata, tutoʻatasi suʻesuʻega e mautinoa ai e saogalemu mo taumafaina i le lalolagi atoa.

mau faasino

[1] Akaike A, et al. (1998). Aafiaga puipuia o le MKC-231, o se tala maualuga maualuga vavalalata choline uptake enhancer, i luga o le glutamate cytotoxicity i agavaʻa faʻapitoa neura. Jpn J Fale Talavai.

[2] Bessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., & Saito, K. (1996). Aʻafiaga o le tala maualuga maualuga vavalalata filifilia o mea lelei 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) acetoamide luga faʻaletonu o vai maze aʻoaʻoina i isumu. Arzneimittel-Forschung, 46 (4), 369–373.

[3] Murai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., & Itoh, T. (1994). O le MKC-231, o se faʻamalosiʻau i le filifilia o le choline, o loʻo faʻamalosia ai le le lava o le manatuaina o galuega ma faʻaititia ai le hippocampal acetylcholine na faʻaosoina e le ethylcholine aziridinium ion i isumu. Tusi o talafaʻasolopito o Neural Transmission, 98 (1), 1–13. Doi: 10.1007 / bf01277590.

[4] Takashina K, Bessho T, Mori R, Eguchi J, Saito K. MKC-231, o se vailaʻau faʻaauau le faʻaaogaina o le koline: (2) Aafiaga i le tuufaatasia ma le faamatuu atu o le acetylcholine i isumu na togafitia AF64A. J Neural Transm (Vienna). 2008 Iulai; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. PubMed PMID: 18446264.

[5] Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Mulimuli ane le faʻaalia i le faʻaauau le gaʻo faʻaleleia MKC-231 e feteʻenaʻi le phencyclidine-faaosofia amioga amio ma faʻaititia o septal cholinergic neurons i isumu. Eur Neuropsychopharmacol. 2007 Setema; 17 (9): 616-26. PubMed PMID: 17467960.

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